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The purpose of this position is to assist in the research of therapies for pancreatic cancer in the Division of Translational Research in the Department of Surgery. This position will assist in drug testing and assessment of cell viability from various species using sterile technique, cell culture, and knowledge of pancreatic disease. The researchers in the department will represent a critical resource for the assessment of assays and results as required to support the advancement of pancreatic cancer pre-clinical and research studies.
Specific duties include:
Experiment Design, Execution and Analysis (85%)
- Perform screening of virus library.
- Molecular biology analyses
- Perform orthotopic pancreatic cancer survival surgeries and tumor transplants on animals
- Evaluate the effect of therapeutics on cells, tissue samples, and in animal models
- Conduct assays to assess the viability of cancer cells with different molecules and supporting activities.
- Maintenance and treatment of cells in culture
- Design and troubleshoot for new techniques and assays for the assessment of pancreatic cancer therapies and cell viability
- Analyze, summarize and prepare pancreatic cancer data for publication
Laboratory Management (10%)
- Maintain laboratory safety, ensuring the lab is compliant with appropriate safety regulations, and lab specific protocols are established and followed. Ensure lab members are trained in the specific competencies and comply with lab safety regulations.
- Perform validation exercises for all aspects of reagent and supply preparation and processing
- Ensure compliance with record keeping and safety training
- Mentor, train, and supervise undergraduate students.
Literature review, R&D, and additional duties (5%)
- Review relevant research literature to facilitate job performance
- Assist with ongoing R&D operations as time allows and as assigned by PI
All required qualifications must be documented on application materials.
- Master’s degree in biologically related field and two years of experience working in a biological lab or a BS/BA and 4 years of related experience.
- Demonstrated experience in molecular biology, cell biology or related field.
- Ability to conduct experiments independently or with minimal supervision.
- Must be able to stand at a laboratory bench or hood for extended periods of time and lift up to 40 lbs.
- Must be able to work flexible hours as needed by project.
- Experience writing and editing scientific papers for publication. Excellent verbal and written communication skills are essential.
- Graduate-level coursework
- Previous experience working in a laboratory setting with various procedures performed following proper biological safety requirements for BSL2
- Experience using the following equipment is preferred: fluorometer, spectrophotometer, spectrometer, centrifuge, speed-vac, microscopes, biological safety cabinet, autoclave, incubators, pipetman, electronic pipet, digital balance, centrifuges, lab chillers and water baths, fume hoods, gas cylinders, pH meter, sonicator, flow cytometer, 7300 Real-Time PCR System, etc.
The Department of Surgery consists of 77 faculty (60 clinical faculty members), approximately 36 fellows and 54 residents. The Department of Surgery has a rich history of renowned basic and clinical science research, distinguishing itself as an academic and clinical center of excellence. We are committed to engaged scholarship and excellence in teaching. Since 1916, the Department of Surgery has been providing innovative and compassionate patient care. The Department of Surgery strives to provide a productive work environment for women and men from varying racial, ethnic, social, and national backgrounds.